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Changes in Alternative Splicing as Pharmacodynamic Markers for Sudemycin D6
OBJECTIVE: The aim of the study was to define pharmacodynamic markers for sudemycin D6, an experimental cancer drug that changes alternative splicing in human blood. METHODS: Blood samples from 12 donors were incubated with sudemycin D6 for up to 24 hours, and at several time points total RNA from l...
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| Publicado en: | Biomark Insights |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
SAGE Publications
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5598794/ https://ncbi.nlm.nih.gov/pubmed/28932105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271917730557 |
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