Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Accumulating evidence reveals that DEP-domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in the pathogenesis and progression of many tumors. However, the expression level of DEPTOR and its function in the tumorigenesis of osteosarcoma (OS) remain unknown. In this study, we cond...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Hu, Binwu, Lv, Xiao, Gao, Feng, Chen, Songfeng, Wang, Shangyu, Qing, Xiangcheng, Liu, Jianxiang, Wang, Baichuan, Shao, Zengwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://ncbi.nlm.nih.gov/pubmed/28932123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S143518
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