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Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Accumulating evidence reveals that DEP-domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in the pathogenesis and progression of many tumors. However, the expression level of DEPTOR and its function in the tumorigenesis of osteosarcoma (OS) remain unknown. In this study, we cond...

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書誌詳細
出版年:Onco Targets Ther
主要な著者: Hu, Binwu, Lv, Xiao, Gao, Feng, Chen, Songfeng, Wang, Shangyu, Qing, Xiangcheng, Liu, Jianxiang, Wang, Baichuan, Shao, Zengwu
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://ncbi.nlm.nih.gov/pubmed/28932123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S143518
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