Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Accumulating evidence reveals that DEP-domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in the pathogenesis and progression of many tumors. However, the expression level of DEPTOR and its function in the tumorigenesis of osteosarcoma (OS) remain unknown. In this study, we cond...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Hu, Binwu, Lv, Xiao, Gao, Feng, Chen, Songfeng, Wang, Shangyu, Qing, Xiangcheng, Liu, Jianxiang, Wang, Baichuan, Shao, Zengwu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://ncbi.nlm.nih.gov/pubmed/28932123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S143518
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