Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

Accumulating evidence reveals that DEP-domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in the pathogenesis and progression of many tumors. However, the expression level of DEPTOR and its function in the tumorigenesis of osteosarcoma (OS) remain unknown. In this study, we cond...

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Библиографические подробности
Опубликовано в: :Onco Targets Ther
Главные авторы: Hu, Binwu, Lv, Xiao, Gao, Feng, Chen, Songfeng, Wang, Shangyu, Qing, Xiangcheng, Liu, Jianxiang, Wang, Baichuan, Shao, Zengwu
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2017
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598754/
https://ncbi.nlm.nih.gov/pubmed/28932123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S143518
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