Chitosan nanoparticles and quercetin modulate gene expression and prevent the genotoxicity of aflatoxin B(1) in rat liver

The aims of the current study were to prepare chitosan nanoparticles (CNPs) and to evaluate its protective role alone or in combination with quercetin (Q) against AFB(1)-induce cytotoxicity in rats. Male Sprague-Dawley rats were divided into 12 groups and treated orally for 4 weeks as follow: the co...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Rep
Hauptverfasser: Abdel-Wahhab, Mosaad A., Aljawish, Abdulhadi, El-Nekeety, Aziza A., Abdel-Aiezm, Sekena H., Abdel-Kader, Heba A.M., Rihn, Bertrand H., Joubert, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598511/
https://ncbi.nlm.nih.gov/pubmed/28962409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.05.007
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