Chitosan nanoparticles and quercetin modulate gene expression and prevent the genotoxicity of aflatoxin B1 in rat liver

The aims of the current study were to prepare chitosan nanoparticles (CNPs) and to evaluate its protective role alone or in combination with quercetin (Q) against AFB1-induce cytotoxicity in rats. Male Sprague-Dawley rats were divided into 12 groups and treated orally for 4 weeks as follow: the cont...

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Main Authors: Mosaad A. Abdel-Wahhab, Abdulhadi Aljawish, Aziza A. El-Nekeety, Sekena H. Abdel-Aiezm, Heba A.M. Abdel-Kader, Bertrand H. Rihn, Olivier Joubert
格式: Artigo
語言:Inglês
出版: Elsevier 2015-01-01
叢編:Toxicology Reports
主題:
Aflatoxin B1
Chitosan nanoparticles
Quercetin
Genotoxicity
Liver
Gene expression
在線閱讀:http://www.sciencedirect.com/science/article/pii/S221475001500061X
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