Estrogen receptor α and aryl hydrocarbon receptor cross-talk in a transfected hepatoma cell line (HepG2) exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

The prototype dioxin congener 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is known to exert anti-estrogenic effects via activation of the aryl hydrocarbon receptor (AhR) by interfering with the regulation of oestrogen homeostasis and the estrogen receptor α (ERα) signalling pathway. The AhR/ER cross-...

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Publicado en:Toxicol Rep
Main Authors: Göttel, Manuela, Le Corre, Ludovic, Dumont, Coralie, Schrenk, Dieter, Chagnon, Marie-Christine
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598243/
https://ncbi.nlm.nih.gov/pubmed/28962316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.09.016
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