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Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

BACKGROUND: A highly efficacious vaccine is needed for malaria control and eradication. Immunization with Plasmodium falciparum NF54 parasites under chemoprophylaxis (chemoprophylaxis and sporozoite (CPS)-immunization) induces the most efficient long-lasting protection against a homologous parasite....

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Walk, Jona, Reuling, Isaie J., Behet, Marije C., Meerstein-Kessel, Lisette, Graumans, Wouter, van Gemert, Geert-Jan, Siebelink-Stoter, Rianne, van de Vegte-Bolmer, Marga, Janssen, Thorsten, Teelen, Karina, de Wilt, Johannes H. W., de Mast, Quirijn, van der Ven, André J., Diez Benavente, Ernest, Campino, Susana, Clark, Taane G., Huynen, Martijn A., Hermsen, Cornelus C., Bijker, Else M., Scholzen, Anja, Sauerwein, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598044/
https://ncbi.nlm.nih.gov/pubmed/28903777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0923-4
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