Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

BACKGROUND: A highly efficacious vaccine is needed for malaria control and eradication. Immunization with Plasmodium falciparum NF54 parasites under chemoprophylaxis (chemoprophylaxis and sporozoite (CPS)-immunization) induces the most efficient long-lasting protection against a homologous parasite....

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Bibliografski detalji
Izdano u:BMC Med
Glavni autori: Walk, Jona, Reuling, Isaie J., Behet, Marije C., Meerstein-Kessel, Lisette, Graumans, Wouter, van Gemert, Geert-Jan, Siebelink-Stoter, Rianne, van de Vegte-Bolmer, Marga, Janssen, Thorsten, Teelen, Karina, de Wilt, Johannes H. W., de Mast, Quirijn, van der Ven, André J., Diez Benavente, Ernest, Campino, Susana, Clark, Taane G., Huynen, Martijn A., Hermsen, Cornelus C., Bijker, Else M., Scholzen, Anja, Sauerwein, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598044/
https://ncbi.nlm.nih.gov/pubmed/28903777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0923-4
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