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Take your PIKK: tumour viruses and DNA damage response pathways
Viruses regulate cellular processes to facilitate viral replication. Manipulation of nuclear proteins and pathways by nuclear replicating viruses often causes cellular genome instability that contributes to transformation. The cellular DNA damage response (DDR) safeguards the host to maintain genome...
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Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Royal Society
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5597736/ https://ncbi.nlm.nih.gov/pubmed/28893936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0269 |
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