Bioanalytical development and validation of liquid chromatographic–tandem mass spectrometric methods for the quantification of total and free cefazolin in human plasma and cord blood

OBJECTIVES: Cefazolin is a commonly prescribed β-lactam antibiotic for prophylaxis against skin infections following surgery, including caesarean sections. Assessment of maternal and neonatal exposure is important for correlating drug concentrations to clinical outcomes. Thus, bioanalytical methods...

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發表在:Pract Lab Med
Main Authors: Crutchfield, Christopher A., Marzinke, Mark A.
格式: Artigo
語言:Inglês
出版: Elsevier 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597705/
https://ncbi.nlm.nih.gov/pubmed/28932794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2015.03.003
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