MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance

Among solid tumors, hepatocellular carcinoma (HCC) emerges as a prototypical therapy-resistant tumor. Considering the emerging sorafenib resistance crisis in HCC, future studies are urgently required to overcome resistance. Recently noncoding RNAs (ncRNAs) have emerged as significant regulators in s...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Awan, Faryal Mehwish, Naz, Anam, Obaid, Ayesha, Ikram, Aqsa, Ali, Amjad, Ahmad, Jamil, Naveed, Abdul Khaliq, Janjua, Hussnain Ahmed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597599/
https://ncbi.nlm.nih.gov/pubmed/28904393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11943-1
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