Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics Approach

Autophagy, an evolutionary conserved multifaceted lysosome-mediated bulk degradation system, plays a vital role in liver pathologies including hepatocellular carcinoma (HCC). Post-translational modifications (PTMs) and genetic variations in autophagy components have emerged as significant determinan...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Awan, Faryal Mehwish, Obaid, Ayesha, Ikram, Aqsa, Janjua, Hussnain Ahmed
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297772/
https://ncbi.nlm.nih.gov/pubmed/28085066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010139
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items