AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models

Glioblastoma multiforme (GBM) is an aggressive, malignant cancer Johnson and O’Neill (J Neurooncol 107: 359–364, 2012). An extract from the winter cherry plant (Withania somnifera), AshwaMAX, is concentrated (4.3 %) for Withaferin A; a steroidal lactone that inhibits cancer cells Vanden Berghe et al...

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Udgivet i:J Neurooncol
Main Authors: Chang, Edwin, Pohling, Christoph, Natarajan, Arutselvan, Witney, Timothy H., Kaur, Jasdeep, Xu, Lingyun, Gowrishankar, Gayatri, D’Souza, Aloma L, Murty, Surya, Schick, Sophie, Chen, Liyin, Wu, Nicholas, Khaw, Phoo, Mischel, Paul, Abbasi, Taher, Usmani, Shahabuddin, Mallick, Parag, Gambhir, Sanjiv S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597337/
https://ncbi.nlm.nih.gov/pubmed/26650066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-1972-1
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