Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells

The short F-actins in the red blood cell (RBC) membrane skeleton are coated along their lengths by an equimolar combination of two tropomyosin isoforms, Tpm1.9 and Tpm3.1. We hypothesized that tropomyosin’s ability to stabilize F-actin regulates RBC morphology and mechanical properties. To test this...

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Pubblicato in:Mol Biol Cell
Autori principali: Sui, Zhenhua, Gokhin, David S., Nowak, Roberta B., Guo, Xinhua, An, Xiuli, Fowler, Velia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597325/
https://ncbi.nlm.nih.gov/pubmed/28720661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0699
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