Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells

The short F-actins in the red blood cell (RBC) membrane skeleton are coated along their lengths by an equimolar combination of two tropomyosin isoforms, Tpm1.9 and Tpm3.1. We hypothesized that tropomyosin’s ability to stabilize F-actin regulates RBC morphology and mechanical properties. To test this...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Sui, Zhenhua, Gokhin, David S., Nowak, Roberta B., Guo, Xinhua, An, Xiuli, Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597325/
https://ncbi.nlm.nih.gov/pubmed/28720661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0699
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