Lamin A and microtubules collaborate to maintain nuclear morphology

Lamin A (LA) is a critical structural component of the nuclear lamina. Mutations within the LA gene (LMNA) lead to several human disorders, most striking of which is Hutchinson-Gilford Progeria Syndrome (HGPS), a premature aging disorder. HGPS cells are best characterized by an abnormal nuclear morp...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleus
Autori principali: Tariq, Zeshan, Zhang, Haoyue, Chia-Liu, Alexander, Shen, Yang, Gete, Yantenew, Xiong, Zheng-Mei, Tocheny, Claire, Campanello, Leonard, Wu, Di, Losert, Wolfgang, Cao, Kan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597299/
https://ncbi.nlm.nih.gov/pubmed/28557611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2017.1320460
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