Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia

Macrophages are essential for the inflammatory response after an ischemic insult and thereby influence tissue recovery. For the oxygen sensing prolyl-4-hydroxylase domain enzyme (PHD) 2 a clear impact on the macrophage-mediated arteriogenic response after hind-limb ischemia has been demonstrated pre...

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Vydáno v:Cell Death Dis
Hlavní autoři: Beneke, Angelika, Guentsch, Annemarie, Hillemann, Annette, Zieseniss, Anke, Swain, Lija, Katschinski, Dörthe M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596563/
https://ncbi.nlm.nih.gov/pubmed/28796258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.375
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