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TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A

Autophagy is a highly inducible system of intracellular degradation that occurs in lysosomes or vacuoles. Transmembrane 74 (TMEM74) has been shown to induce autophagy. However, the mechanism by which TMEM74 stimulates autophagy and the impacts of TMEM74-induced autophagy on tumor cell survival remai...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sun, Yizhe, Chen, Yingyu, Zhang, Jingyu, Cao, Lulu, He, Minwei, Liu, Xi, Zhao, Ning, Yin, Ang, Huang, He, Wang, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596558/
https://ncbi.nlm.nih.gov/pubmed/29048433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.370
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