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MicroRNA-34/449 targets IGFBP-3 and attenuates airway remodeling by suppressing Nur77-mediated autophagy

Autophagy plays critical roles in airway inflammation and fibrosis-mediated airway remodeling and many factors including proinflammatory cytokines and inflammation related pathways are involved in the process. The aim of the present study was to examine the role of epithelial microRNAs (miRNAs) in a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yin, Huiming, Zhang, Shu, Sun, Yahong, Li, Sha, Ning, Yunye, Dong, Yuchao, Shang, Yan, Bai, Chong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596548/
https://ncbi.nlm.nih.gov/pubmed/28796252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.357
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