Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer

Olfactory dysfunction is a common symptom associated with neurodegenerative diseases including Alzheimer’s disease (AD). Although evidence exists to suggest that peripheral olfactory organs are involved in the olfactory dysfunction that accompanies AD pathology, the underlying mechanisms are not ful...

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Publicado en:Cell Death Dis
Autores principales: Yoo, Seung-Jun, Lee, Ji-Hye, Kim, So Yeun, Son, Gowoon, Kim, Jae Yeon, Cho, Bongki, Yu, Seong-Woon, Chang, Keun-A, Suh, Yoo-Hun, Moon, Cheil
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596540/
https://ncbi.nlm.nih.gov/pubmed/28796251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.349
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