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Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging

Rationale: Ultrasound-mediated opening of the Blood-Brain Barrier(BBB) has shown exciting potential for the treatment of Alzheimer's disease(AD). Studies in transgenic mouse models have shown that this approach can reduce plaque pathology and improve spatial memory. Before clinical translation...

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Dades bibliogràfiques
Publicat a:Theranostics
Autors principals: O'Reilly, Meaghan Anne, Jones, Ryan Matthew, Barrett, Edward, Schwab, Anthony, Head, Elizabeth, Hynynen, Kullervo
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596444/
https://ncbi.nlm.nih.gov/pubmed/28912896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.20621
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