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Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging

Rationale: Ultrasound-mediated opening of the Blood-Brain Barrier(BBB) has shown exciting potential for the treatment of Alzheimer's disease(AD). Studies in transgenic mouse models have shown that this approach can reduce plaque pathology and improve spatial memory. Before clinical translation...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: O'Reilly, Meaghan Anne, Jones, Ryan Matthew, Barrett, Edward, Schwab, Anthony, Head, Elizabeth, Hynynen, Kullervo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596444/
https://ncbi.nlm.nih.gov/pubmed/28912896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.20621
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