MicroRNAs-143 and -145 induce epithelial to mesenchymal transition and modulate the expression of junction proteins

Transforming growth factor (TGF)-β is one of the major inducers of epithelial to mesenchymal transition (EMT), a crucial program that has a critical role in promoting carcinoma’s metastasis formation. MicroRNAs-143 and -145, which are both TGF-β direct transcriptional targets, are essential for the...

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Publicat a:Cell Death Differ
Autors principals: Avalle, Lidia, Incarnato, Danny, Savino, Aurora, Gai, Marta, Marino, Francesca, Pensa, Sara, Barbieri, Isaia, Stadler, Michael B, Provero, Paolo, Oliviero, Salvatore, Poli, Valeria
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596419/
https://ncbi.nlm.nih.gov/pubmed/28644441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.103
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