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Towards a systematic assessment of assay interference: Identification of extensively tested compounds with high assay promiscuity

A large-scale statistical analysis of hit rates of extensively assayed compounds is presented to provide a basis for a further assessment of assay interference potential and multi-target activities. A special feature of this investigation has been the inclusion of compound series information in acti...

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Publicado en:F1000Res
Autores principales: Gilberg, Erik, Stumpfe, Dagmar, Bajorath, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: F1000Research 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596351/
https://ncbi.nlm.nih.gov/pubmed/28928939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12370.2
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