Metabolic Stress-Induced Activation of AMPK and Inhibition of Constitutive Phosphoproteins Controlling Smooth Muscle Contraction: Evidence for Smooth Muscle Fatigue?

Metabolic stress diminishes smooth muscle contractile strength by a poorly defined mechanism. To test the hypothesis that metabolic stress activates a compensatory cell signaling program to reversibly downregulate contraction, arterial rings and bladder muscle strips in vitro were deprived of O(2) a...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Smith, Corey A., Miner, Amy S., Barbee, Robert W., Ratz, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596101/
https://ncbi.nlm.nih.gov/pubmed/28943852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00681
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