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The pharmacokinetic interaction between ivacaftor and ritonavir in healthy volunteers

AIMS: The aim of this study was to determine the pharmacokinetic interaction between ivacaftor and ritonavir. METHODS: A liquid chromatography mass spectrometry (LC–MS) method was developed for the measurement of ivacaftor in plasma. An open‐label, sequential, cross‐over study was conducted with 12...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Liddy, Anne Marie, McLaughlin, Gavin, Schmitz, Susanne, D'Arcy, Deirdre M., Barry, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595953/
https://ncbi.nlm.nih.gov/pubmed/28477428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13324
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