The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis

Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface recepto...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Kosack, Lindsay, Gawish, Riem, Lercher, Alexander, Vilagos, Bojan, Hladik, Anastasiya, Lakovits, Karin, Bhattacharya, Anannya, Schliehe, Christopher, Mesteri, Ildiko, Knapp, Sylvia, Bergthaler, Andreas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595927/
https://ncbi.nlm.nih.gov/pubmed/28900132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10637-y
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