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The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis

Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface recepto...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kosack, Lindsay, Gawish, Riem, Lercher, Alexander, Vilagos, Bojan, Hladik, Anastasiya, Lakovits, Karin, Bhattacharya, Anannya, Schliehe, Christopher, Mesteri, Ildiko, Knapp, Sylvia, Bergthaler, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595927/
https://ncbi.nlm.nih.gov/pubmed/28900132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10637-y
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