Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload

Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....

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發表在:Sci Rep
Main Authors: Slavic, Svetlana, Ford, Kristopher, Modert, Magalie, Becirovic, Amarela, Handschuh, Stephan, Baierl, Andreas, Katica, Nejla, Zeitz, Ute, Erben, Reinhold G., Andrukhova, Olena
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595838/
https://ncbi.nlm.nih.gov/pubmed/28900153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10140-4
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