Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload

Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Slavic, Svetlana, Ford, Kristopher, Modert, Magalie, Becirovic, Amarela, Handschuh, Stephan, Baierl, Andreas, Katica, Nejla, Zeitz, Ute, Erben, Reinhold G., Andrukhova, Olena
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595838/
https://ncbi.nlm.nih.gov/pubmed/28900153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10140-4
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