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Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload
Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Sci Rep |
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Prif Awduron: | , , , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Nature Publishing Group UK
2017
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595838/ https://ncbi.nlm.nih.gov/pubmed/28900153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10140-4 |
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