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Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload

Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Slavic, Svetlana, Ford, Kristopher, Modert, Magalie, Becirovic, Amarela, Handschuh, Stephan, Baierl, Andreas, Katica, Nejla, Zeitz, Ute, Erben, Reinhold G., Andrukhova, Olena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595838/
https://ncbi.nlm.nih.gov/pubmed/28900153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10140-4
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