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Enhanced transport of plant‐produced rabies single‐chain antibody‐RVG peptide fusion protein across an in cellulo blood–brain barrier device

The biomedical applications of antibody engineering are developing rapidly and have been expanded to plant expression platforms. In this study, we have generated a novel antibody molecule in planta for targeted delivery across the blood–brain barrier (BBB). Rabies virus (RABV) is a neurotropic virus...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Phoolcharoen, Waranyoo, Prehaud, Christophe, van Dolleweerd, Craig J., Both, Leonard, da Costa, Anaelle, Lafon, Monique, Ma, Julian K‐C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595719/
https://ncbi.nlm.nih.gov/pubmed/28273388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12719
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