Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP). The purpose here was to establish a plant-based production system for a chimeric mouse-hum...

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Main Authors: Both, Leonard, van Dolleweerd, Craig, Wright, Edward, Banyard, Ashley C., Bulmer-Thomas, Bianca, Selden, David, Altmann, Friedrich, Fooks, Anthony R., Ma, Julian K.-C.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633812/
https://ncbi.nlm.nih.gov/pubmed/23371065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-219964
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