Small RNAs induce the activation of the pro‐inflammatory TLR7 signaling pathway in aged rat kidney

We have recently reported that TLR‐related genes, including TLR7, are upregulated during aging. However, the role of TLR7 and its endogenous ligand in inflammation related to aging is not well defined. Here, we established that small RNAs trigger age‐related renal inflammation via TLR7 signaling pat...

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Vydáno v:Aging Cell
Hlavní autoři: Lee, Eun Kyeong, Chung, Ki Wung, Kim, Ye Ra, Ha, Sugyeong, Kim, Sung Dae, Kim, Dae Hyun, Jung, Kyung Jin, Lee, Bonggi, Im, Eunok, Yu, Byung Pal, Chung, Hae Young
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595700/
https://ncbi.nlm.nih.gov/pubmed/28665028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12629
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