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Combined deficiency of the Cnr1 and Cnr2 receptors protects against age‐related bone loss by osteoclast inhibition

The endocannabinoid system plays a role in regulating bone mass and bone cell activity and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak bone mass and age‐related bone loss. As the Cnr1 and Cnr2 receptors have limited homology and are activated by different...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Sophocleous, Antonia, Marino, Silvia, Kabir, Dilruba, Ralston, Stuart H., Idris, Aymen I.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595693/
https://ncbi.nlm.nih.gov/pubmed/28752643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12638
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