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The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation

The poly(A) leader at the 5’-untranslated region (5’-UTR) is an unusually striking feature of all poxvirus mRNAs transcribed after viral DNA replication (post-replicative mRNAs). These poly(A) leaders are non-templated and of heterogeneous lengths; and their function during poxvirus infection remain...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Dhungel, Pragyesh, Cao, Shuai, Yang, Zhilong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595341/
https://ncbi.nlm.nih.gov/pubmed/28854224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006602
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