A Nanosystem of Amphiphilic Oligopeptide-Drug Conjugate Actualizing Both αvβ3 Targeting and Reduction-Triggered Release for Maytansinoid

To design a prodrug-based self-assembling nanosystem with both ligand targeting and stimuli-responsive features, and elucidate the superiority of each targeting strategy and the synergistic effect between them, we synthesized four small molecule amphiphilic peptide-drug conjugates (APDCs) using mayt...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Liang, Yanqin, Li, Suxin, Wang, Xiaoyou, He, Bo, He, Bing, Dai, Wenbing, Zhang, Hua, Wang, Xueqing, Wang, Yiguang, Zhou, Demin, Zhang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595133/
https://ncbi.nlm.nih.gov/pubmed/28900511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.20242
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