Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates

Antibody-drug conjugates (ADCs) are of great interest as targeted cancer therapeutics. Preparation of ADCs for early stage screening is constrained by purification and biochemical analysis techniques that necessitate burdensome quantities of antibody. Here we describe a method, developed for the may...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:MAbs
मुख्य लेखकों: Catcott, Kalli C., McShea, Molly A., Bialucha, Carl Uli, Miller, Kathy L., Hicks, Stuart W., Saxena, Parmita, Gesner, Thomas G., Woldegiorgis, Mikias, Lewis, Megan E., Bai, Chen, Fleming, Michael S., Ettenberg, Seth A., Erickson, Hans K., Yoder, Nicholas C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2016
विषय:
Reports
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966849/
https://ncbi.nlm.nih.gov/pubmed/26752675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1134408
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