Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles

Delivery of macromolecular drugs to the brain is impeded by the blood brain barrier. The recruitment of leukocytes to lesions in the brain, a typical feature of neuroinflammation response which occurs in cerebral ischemia, offers a unique opportunity to deliver drugs to inflammation sites in the bra...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhang, Chun, Ling, Cheng-li, Pang, Liang, Wang, Qi, Liu, Jing-xin, Wang, Bing-shan, Liang, Jian-ming, Guo, Yi-zhen, Qin, Jing, Wang, Jian-xin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595130/
https://ncbi.nlm.nih.gov/pubmed/28900508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19979
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