Identification of Novel Epitopes with Agonistic Activity for the Development of Tumor Immunotherapy Targeting TRAIL-R1

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-1/2 (TRAIL-R1/R2), also known as death receptors, are expressed in a wide variety of tumor cells. Although TRAIL can induce cell apoptosis by engaging its cognate TRAIL-R1/R2, some tumor cells are or become resistant to TRAIL t...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Guo, Lu, Sun, Xin, Hao, Zhichao, Huang, Jingjing, Han, Xiaojian, You, Yajie, Li, Yaying, Shen, Meiying, Ozawa, Tatsuhiko, Kishi, Hiroyuki, Muraguchi, Atsushi, Jin, Aishun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595084/
https://ncbi.nlm.nih.gov/pubmed/28900492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19918
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