TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo

Agonistic tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-receptor-specific antibodies are attractive antitumor therapeutics. Recently, our group has generated several human monoclonal antibodies (mAbs) to TRAIL-receptor-1 (TRAIL-R1) (TR1-IgGs) using ISAAC technology. However,...

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Vydáno v:Oncoimmunology
Hlavní autoři: Piao, Xiuhong, Ozawa, Tatsuhiko, Hamana, Hiroshi, Shitaoka, Kiyomi, Jin, Aishun, Kishi, Hiroyuki, Muraguchi, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910746/
https://ncbi.nlm.nih.gov/pubmed/27467950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1131380
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