Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G

Our understanding of the mechanisms underlying inherited forms of inner ear deficits has considerably improved during the past 20 y, but we are still far from curative treatments. We investigated gene replacement as a strategy for restoring inner ear functions in a mouse model of Usher syndrome type...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Emptoz, Alice, Michel, Vincent, Lelli, Andrea, Akil, Omar, Boutet de Monvel, Jacques, Lahlou, Ghizlene, Meyer, Anaïs, Dupont, Typhaine, Nouaille, Sylvie, Ey, Elody, Franca de Barros, Filipa, Beraneck, Mathieu, Dulon, Didier, Hardelin, Jean-Pierre, Lustig, Lawrence, Avan, Paul, Petit, Christine, Safieddine, Saaid
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594693/
https://ncbi.nlm.nih.gov/pubmed/28835534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708894114
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