Loading...

Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase

Noncanonical DNA structures that stall DNA replication can cause errors in genomic DNA. Here, we investigated how the noncanonical structures formed by sequences in genes associated with a number of diseases impacted DNA polymerization by the Klenow fragment of DNA polymerase. Replication of a DNA s...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Takahashi, Shuntaro, Brazier, John A., Sugimoto, Naoki
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594654/
https://ncbi.nlm.nih.gov/pubmed/28827350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704258114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!