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Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase
Noncanonical DNA structures that stall DNA replication can cause errors in genomic DNA. Here, we investigated how the noncanonical structures formed by sequences in genes associated with a number of diseases impacted DNA polymerization by the Klenow fragment of DNA polymerase. Replication of a DNA s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5594654/ https://ncbi.nlm.nih.gov/pubmed/28827350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704258114 |
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