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Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization

Age-related macular degeneration (AMD) is the most common cause of blindness for individuals age 50 and above in the developed world. Abnormal growth of choroidal blood vessels, or choroidal neovascularization (CNV), is a hallmark of the neovascular (wet) form of advanced AMD and leads to significan...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hasegawa, Eiichi, Inafuku, Saori, Mulki, Lama, Okunuki, Yoko, Yanai, Ryoji, Smith, Kaylee E., Kim, Clifford B., Klokman, Garrett, Bielenberg, Diane R., Puli, Narender, Falck, John R., Husain, Deeba, Miller, Joan W., Edin, Matthew L., Zeldin, Darryl C., Lee, Kin Sing Stephen, Hammock, Bruce D., Schunck, Wolf-Hagen, Connor, Kip M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594641/
https://ncbi.nlm.nih.gov/pubmed/28827330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620898114
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