Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines

Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baba, Koichi, Kitajima, Yoshihiko, Miyake, Shuusuke, Nakamura, Jun, Wakiyama, Kota, Sato, Hirofumi, Okuyama, Keiichiro, Kitagawa, Hiroshi, Tanaka, Tomokazu, Hiraki, Masatsugu, Yanagihara, Kazuyoshi, Noshiro, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594024/
https://ncbi.nlm.nih.gov/pubmed/28894280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11769-x
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