The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions

Gastric cancer grows under a hypoxic environment. HIF-1α is known to play an important role in controlling the production of reactive oxygen species (ROS) in the mitochondria under hypoxic conditions. We previously established HIF-1α knockdown (KD) cells and control (SC) cells in the 58As9 gastric c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tanaka, Tomokazu, Kitajima, Yoshihiko, Miyake, Shuusuke, Yanagihara, Kazuyoshi, Hara, Hiromitsu, Nishijima-Matsunobu, Aki, Baba, Koichi, Shida, Masaaki, Wakiyama, Kota, Nakamura, Jun, Noshiro, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560388/
https://ncbi.nlm.nih.gov/pubmed/26339797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137257
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