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Impact of protein O-GlcNAcylation on neural tube malformation in diabetic embryopathy
Diabetes mellitus in early pregnancy can cause neural tube defects (NTDs) in embryos by perturbing protein activity, causing cellular stress, and increasing programmed cell death (apoptosis) in the tissues required for neurulation. Hyperglycemia augments a branch pathway in glycolysis, the hexosamin...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593976/ https://ncbi.nlm.nih.gov/pubmed/28894244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11655-6 |
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