Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model

LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat fibrosarcoma model. The treatment was T-cell dependent, and also resulted in an...

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Publicat a:Oncoimmunology
Autors principals: Nestvold, Janne, Wang, Meng-Yu, Camilio, Ketil A., Zinöcker, Severin, Tjelle, Torunn Elisabeth, Lindberg, Alf, Haug, Bengt Erik, Kvalheim, Gunnar, Sveinbjørnsson, Baldur, Rekdal, Øystein
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593701/
https://ncbi.nlm.nih.gov/pubmed/28920000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338236
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