The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells

Host defense peptides (HDPs) are naturally occurring molecules found in most species, in which they play a significant role in the first line defense against intruding pathogens, and several HDPs have been shown to possess anticancer activity. Structure-activity relationship studies on the HDP bovin...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Eike, Liv-Marie, Yang, Nannan, Rekdal, Øystein, Sveinbjørnsson, Baldur
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741498/
https://ncbi.nlm.nih.gov/pubmed/26472184
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