Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib

The tyrosine kinase inhibitor erlotinib targets the receptor of epidermal growth factor (EGFR) involved in development of hepatocellular carcinoma (HCC). Although inefficient in established HCC, erlotinib has been recently proposed for HCC chemoprevention. Since Cyp3A4 and Cyp1A2 enzymes metabolize...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Rohr-Udilova, Nataliya, Klinglmüller, Florian, Seif, Martha, Hayden, Hubert, Bilban, Martin, Pinter, Matthias, Stolze, Klaus, Sieghart, Wolfgang, Peck-Radosavljevic, Markus, Trauner, Michael
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593629/
https://ncbi.nlm.nih.gov/pubmed/28915658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19055
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