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Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome
PURPOSE: To investigate how necroptosisis, i.e. programmed necrosis, is involved in MODS, and to examine whether Nec-1, a specific necroptosis inhibitor, ameliorates multiorgan injury in MODS. EXPERIMENTAL DESIGN: A model of MODS was established in six-week old SD rats using fracture trauma followed...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593618/ https://ncbi.nlm.nih.gov/pubmed/28915647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18252 |
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